Are Dietary Indices Associated with Polycystic Ovary Syndrome and Its Phenotypes? A Preliminary Study

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder which impairs ovarian function. The adherence to healthy dietary patterns and physical exercise are the first line of recommended treatment for PCOS patients, but it yet unclear what type diet more adequate. In this case-control study, we explored associations between five quality indices presence PCOS. We enrolled 126 cases 159 controls living in Murcia (Spain). Diagnostic its phenotypes were established following Rotterdam criteria (hyperandrogenism (H), oligoanovulation (O), polycystic ovaries morphology (POM)). used validated food frequency questionnaires calculate scores indices: alternate Healthy Eating index (AHEI), AHEI-2010, relative Mediterranean Dietary Score (rMED), (aMED) Approaches Stop Hypertension (DASH). multivariable logistic regression estimate adjusted odds ratios confidence intervals. analysis, AHEI-2010 was inversely associated with Hyperandrogenism + Oligoanovulation phenotype (ORQ3 vs. Q1 = 0.1; 95% CI: (0.0; 0.9); Pfor trend 0.02). did not find any statistical significant association total anovulatory or ovulatory However, further studies higher sample sizes exploring these among diverse highly warranted.